Zyprexa tablets NOT recommended for splitting.

ZYPREXA is known as an atypical antipsychotic drug used to treat schizophrenia and acute manic episodes associated with bipolar I disorder. Exactly how it works is not known however research states it blocks receptors for several neurotransmitters (chemicals that nerves use to communicate with each other) in the brain. ZYPREXA is used in in adults and children who are at least 13 years old.

This medicine may be only part of a complete program of treatment that also includes counseling and other psychological support programs. Follow your doctor's instructions.

Note: ZYPREXA is not for use in psychotic conditions related to dementia

ZYPREXA is usually taken once a day, with or without food. Keep the tablet in its blister pack or container until you are ready to take it. Use dry hands as the tablet will begin to dissolve right away against moisture. Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing. Swallow several times as the tablet dissolves. If desired, you may drink liquid to help swallow the dissolved tablet.

Patients should inform their doctor if they have any of the following conditions to ensure they can safely take ZYPREXA

• liver disease
• heart disease, high or low blood pressure
• a history of low white blood cell (WBC) counts
• high cholesterol or triglycerides
• a history of heart failure, heart attack, or stroke
• a history of breast cancer
• seizures or epilepsy
• diabetes
• an enlarged prostate or difficulty urinating
• bowel problems
• narrow-angle glaucoma

Serious side effects may include very stiff (rigid) muscles, high fever, tremors, sweating, confusion, fast or uneven heartbeats, slow heart rate, feeling like you might pass out; twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs; trouble speaking or swallowing; dry mouth, thirst, feeling very hot (with or without sweating), urinating less than usual or not at all; high blood sugar (increased thirst, loss of appetite, fruity breath odor, increased urination, drowsiness, dry skin, nausea, and vomiting); sudden numbness or weakness, confusion, or problems with vision, speech, or balance; fever, chills, body aches, flu symptoms, sores in your mouth and throat; swelling in your hands or feet; changes in personality, unusual thoughts or behavior, hallucinations, or thoughts about hurting yourself; or upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about additional side effects that you may experience.